A CASE OF PULMONARY ASPERGILLOSIS IN AN IMMUNOLOGICALLY INTACT 15-YEAR-OLD BOY

  • Nataliya Gabrovska Department of Pulmonary Diseases, Medical University – Sofia, Multiprofile Hospital for Active Treatment of Pul- monary Diseases „St. Sofia“, Sofia, Bulgaria
  • Svetlana Velizarova Department of Pulmonary Diseases, Medical University – Sofia, Multiprofile Hospital for Active Treatment of Pul- monary Diseases „St. Sofia“, Sofia, Bulgaria
  • Albena Spasova Department of Pulmonary Diseases, Medical University – Sofia, Multiprofile Hospital for Active Treatment of Pul- monary Diseases „St. Sofia“, Sofia, Bulgaria
  • Dimitar Kostadinov Department of Pulmonary Diseases, Medical University – Sofia, Multiprofile Hospital for Active Treatment of Pul- monary Diseases „St. Sofia“, Sofia, Bulgaria
  • Nikolay Yanev Department of Pulmonary Diseases, Medical University – Sofia, Multiprofile Hospital for Active Treatment of Pul- monary Diseases „St. Sofia“, Sofia, Bulgaria
  • Hristo Shivachev Department of Paediatric Thoracic Surgery, Paediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine “N. I. Pirogov”, Sofia, Bulgaria
  • Yanko Pahnev Department of Paediatric Thoracic Surgery, Paediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine “N. I. Pirogov”, Sofia, Bulgaria
  • Zdravka Antonova Department of Paediatric Thoracic Surgery, Paediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine “N. I. Pirogov”, Sofia, Bulgaria
  • Prof. Todor Kantardjiev, MD National Centre of Infectious and Parasitic Diseases
Keywords: pulmonary aspergillosis, non-immunocompromised children, clinical presentation, diagnostic tests, treatment

Abstract

Aspergillus is a fungus which could cause a number of infectious and allergic diseases especially in immunocompromised patients.

We report a case of 15-year-old boy with a small post-pneumonic cavity formation in the 3rd segment of the right lung. After conventional intravenous antibiotic treatment the X-ray changes were still persisting. The boy was in good general condition, without intoxication syndrome, with intact immune status. Physical examination was normal except for mild rare cough. The diagnosis was confirmed by imaging, serological and microbiological tests. Oral itraconazole (200 mg daily) was administered for 6 months along with monthly monitoring of the liver function. CT scan controls were performed in the 2nd, 4th and 6th month. Complete resolution of the cavity was observed in the final CT scan. No operative treatment was necessary.

Although  typical for immunocompromised patients, an immunologically intact child without other underlying diseases can also develop pulmonary aspergillosis. Small lesions respond well to conservative treatment without surgery.

Author Biography

Prof. Todor Kantardjiev, MD, National Centre of Infectious and Parasitic Diseases

Director of National Centre of Infectious and Parasitic Diseases;

National Microbiology Consultant

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Published
2019-12-30
How to Cite
Gabrovska, N., Velizarova, S., Spasova, A., Kostadinov, D., Yanev, N., Shivachev, H., Pahnev, Y., Antonova, Z., & Kantardjiev, T. (2019). A CASE OF PULMONARY ASPERGILLOSIS IN AN IMMUNOLOGICALLY INTACT 15-YEAR-OLD BOY. Problems of Infectious and Parasitic Diseases, 47(2), 7-11. Retrieved from http://pipd.ncipd.org/index.php/pipd/article/view/47_2_2-A_CASE_OF_PULMONARY_ASPERGILLOSIS_IN_AN_IMMUNOLOGICALLY_INTACT_15-YEAR-OLD_BOY
Section
Articles

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