BRUCELLOSIS - AN UNKNOWN AND UNDERDIAGNOSED INFECTION IN BULGARIA

Authors

  • Rumiana Nenova, MD National Centre of Infectious and Parasitic Diseases
  • Iskra Tomova National Centre of Infectious and Parasitic Diseases

Keywords:

brucellosis, re-emergence, outbreak, autochthonous, microbiological diagnosis

Abstract

Brucellosis is still the most common zoonosis worldwide. Despite this, it is unknown and underdiagnosed infection in non-endemic areas. For some parts of the world it became a re-emerging infection. After several decades brucellosis re-emerged in Bulgaria. In 2005 an outbreak of imported human cases was detected and soon after, two autochthonous outbreaks occurred (2006 and 2015) with a total of 161 persons diagnosed.

Author Biographies

Rumiana Nenova, MD, National Centre of Infectious and Parasitic Diseases

Dr. RUMIANA NENOVA
National Reference lab on high threat bacterial infections
NCIPD
blvd. Stoletov 44
Sofia, BULGARIA
Tel: + 3592 8319125

Iskra Tomova, National Centre of Infectious and Parasitic Diseases

Iskra Tomova
National Reference lab on high threat bacterial infections
NCIPD
blvd. Stoletov 44
Sofia, BULGARIA
Tel: + 3592 8319125

References

Bruce D. Note on the discovery of a microorganism in Malta fever. Practitioner. 1887; 36:161-170.

Bang B. The etiology of epizootic abortion. J Comp Pathol Ther. 1897; 10:125-149.

Meyer KF, Shaw EB. A comparison of the morphologic, culture and biochemical characteristics of B. abortus and B. melitensis: studies on the genus Brucella nov. gen. I. J Infect Dis. 1920;27: 173-184.

Hudellstone IF. Differentiation of the species of the genus Brucella. Am J Public Health. 1929; 21:491-498.

Buddle MB. Studies on Brucella ovis (n. sp.), a cause of genital disease of sheep in New Zealand and Australia. J Hyg Camb. 1956; 54:351-364.

Stornner HG, Lackman BD. A new species of Brucella isolated from the desert woodrat Neotoma lepida. J Vet Res. 1957; 18:947-951.

Carmichael ВЕ, Bruner DW. Characteristics of a newly recognized species of Brucella responsible for infectious canine abortions. Cornell Vet. 1968; 48:579-592.

Halling SM, Peterson-Burch BD, Bricker BJ et al. Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of B. melitensis and B. suis. J Bacteriol. 2005; 187:2715-2726.

Corbel MJ. International committee on systematic bacteriology subcommittee on the taxonomy of Brucella. Int J Syst Bacteriol. 1988; 38:450-452.

Ross HM, Foster G, Reid RJ et al. Brucella species infection in sea-mammals. Vet Rec. 1994; 2;134(14):359.

Ewalt DR, Payeur JB, Martin BM et al. Characteristics of a Brucella species from a bottlenose dolphin (Tursiops truncatus). J Vet Diagn Invest. 1994; 6:448-452.

Foster G, Osterman BS, Godfroid J et al. Brucella ceti sp. nov. and Brucella pinnipedialis sp. nov. for Brucella strains with cetaceans and seals as their preferred hosts. Int J Syst Evol Microbio. 2007; 57: 2688-2693.

Scholz CH, Hubalek Z, SedlacekI et al. Brucella microti sp. nov., isolated from the common vole Microtus arvalis. Int J Syst Evol Microbio. 2008; 58:375-382.

Scholz HC, Nockler K, Gollner C, Bahn P, Vergnaud G, Tomaso H, et al. Brucella inopinata sp. nov., isolated from a breast implant infection. Int J Syst Evol Microbiol. 2010; 60:801–808.

Tiller RV, Gee JE, Lonsway DR et al. Identification of an unusual Brucella strain (BO2) from a lung biopsy in a 52-year-old patient with chronic destructive pneumonia. BMC Microbiol. 2010; 10:23.

Hofer E, Revilla-Fernández S, Al Dahouk S et al. A potential novel Brucella species isolated from mandibular lymph nodes of red foxes in Austria Vet Microbiol. 2012; 155(1):93-99.

Scholz HC, Revilla-Fernández S, Al Dahouk S et al. Brucella vulpis sp. nov., isolated from mandibular lymph nodes of red foxes (Vulpes vulpes). Int J Syst Evol Microbiol. 2016; 66(5):2090-2098.

Downloads

Published

2017-07-01

How to Cite

Nenova, R., & Tomova, I. (2017). BRUCELLOSIS - AN UNKNOWN AND UNDERDIAGNOSED INFECTION IN BULGARIA . PROBLEMS of Infectious and Parasitic Diseases, 45(1), 5-14. Retrieved from https://pipd.ncipd.org/index.php/pipd/article/view/PIPD_45_1_1_brucellosis-an_unknown_and_underdiagnosed_infection_

Issue

Section

Articles

Most read articles by the same author(s)