FIRST CASES IN BULGARIA WITH PROVEN CANDIDA AURIS IN IMMUNOCOMPROMISED PATIENTS
DOI:
https://doi.org/10.58395/pz7yfj98Keywords:
Candida auris, resistance, antifungalsAbstract
Candida auris is a fungus with pathogenic potential, first isolated in 2009 in Japan. Since then, sporadic cases have been reported, which have increased significantly in recent years.
In Bulgaria, for the first time in 2025, we described almost simultaneously three cases with Candida auris strains isolated from hospitalized patients. All of them were immunocompromised, mainly with cardiovascular problems, but in none of them a fungal isolate from blood stream was obtained. It is probably a question of colonization.
In the National Reference Laboratory of Mycoses at the NCIPD, Candida auris fungal strains were confirmed and tested for susceptibility to antifungals. All showed resistance to Fluconazole.
Given the frequent misidentification of Candida auris, adequate microbiological examination and subsequent appropriate antifungal therapy are necessary, because this fungus is associated with a high mortality rate in immunocompromised individuals, even with initiated treatment.
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Copyright (c) 2025 Lyubomira Boyanova, Zoya Ivanova, Asya Bachvarova (Author)
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