SEROPREVALENCE OF WEST NILE VIRUS IN BULGARIA, 2018

  • Elitsa Panayotova National Centre of Infectious and Parasitic Diseases
  • Prof. Iva Christova, MD National Centre of Infectious and Parasitic Diseases
  • Iva Trifonova National Centre of Infectious and Parasitic Diseases
  • Evgenia Taseva National Centre of Infectious and Parasitic Diseases
  • Teodora Gladnishka National Centre of Infectious and Parasitic Diseases
  • Vladislava Ivanova National Centre of Infectious and Parasitic Diseases
Keywords: West Nile Virus, WNV, seroprevalence, antibodies, neuroinvasive disease

Abstract

In Bulgaria, the first laboratory-confirmed West Nile neuroinvasive disease (WNND) case occurred in 2015 and more cases have been reported ever since. The aim of our study was to track the current circulation of West Nile virus (WNV) in the country. We collected 1830 serum samples from healthy people of every district in Bulgaria. Commercially available ELISA kits were used to detect specific anti-WNV IgG antibodies. All positive samples were tested for specific IgM antibodies using the same method. Possible risk factors were identified by calculating odds ratio. Specific IgG antibodies were detected in 22 of the samples (1.2%, CI 0.8% to 1.8%). No IgM antibodies were detected in the positive samples. The highest seroprevalence rates were found in the districts of Pleven, Varna, Silistra and Yambol. This study showed the continuous circulation and spread of WNV in Bulgaria

Author Biographies

Elitsa Panayotova, National Centre of Infectious and Parasitic Diseases

National reference laboratory of vector-borne infections, listeria and leptospires

Prof. Iva Christova, MD, National Centre of Infectious and Parasitic Diseases

Head of National reference laboratory of vector-borne infections, listeria and leptospires

Iva Trifonova, National Centre of Infectious and Parasitic Diseases

National reference laboratory of vector-borne infections, listeria and leptospires

Evgenia Taseva, National Centre of Infectious and Parasitic Diseases

National reference laboratory of vector-borne infections, listeria and leptospires

Teodora Gladnishka, National Centre of Infectious and Parasitic Diseases

National reference laboratory of vector-borne infections, listeria and leptospires

Vladislava Ivanova, National Centre of Infectious and Parasitic Diseases

National reference laboratory of vector-borne infections, listeria and leptospires

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Published
2019-12-30
How to Cite
Panayotova, E., Christova, I., Trifonova, I., Taseva, E., Gladnishka, T., & Ivanova, V. (2019). SEROPREVALENCE OF WEST NILE VIRUS IN BULGARIA, 2018. Problems of Infectious and Parasitic Diseases, 47(2), 15-17. Retrieved from http://pipd.ncipd.org/index.php/pipd/article/view/47_2-4_SEROPREVALENCE_OF_WEST_NILE_VIRUS_IN_BULGARIA_2018
Section
Articles

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