SEROPREVALENCE OF WEST NILE VIRUS IN BULGARIA, 2018

Authors

  • Elitsa Panayotova National Centre of Infectious and Parasitic Diseases Author
  • Prof. Iva Christova, MD National Centre of Infectious and Parasitic Diseases Author
  • Iva Trifonova National Centre of Infectious and Parasitic Diseases Author
  • Evgenia Taseva National Centre of Infectious and Parasitic Diseases Author
  • Teodora Gladnishka National Centre of Infectious and Parasitic Diseases Author
  • Vladislava Ivanova National Centre of Infectious and Parasitic Diseases Author

DOI:

https://doi.org/10.58395/pipd.v47i2.6

Keywords:

West Nile Virus, WNV, seroprevalence, antibodies, neuroinvasive disease

Abstract

In Bulgaria, the first laboratory-confirmed West Nile neuroinvasive disease (WNND) case occurred in 2015 and more cases have been reported ever since. The aim of our study was to track the current circulation of West Nile virus (WNV) in the country. We collected 1830 serum samples from healthy people of every district in Bulgaria. Commercially available ELISA kits were used to detect specific anti-WNV IgG antibodies. All positive samples were tested for specific IgM antibodies using the same method. Possible risk factors were identified by calculating odds ratio. Specific IgG antibodies were detected in 22 of the samples (1.2%, CI 0.8% to 1.8%). No IgM antibodies were detected in the positive samples. The highest seroprevalence rates were found in the districts of Pleven, Varna, Silistra and Yambol. This study showed the continuous circulation and spread of WNV in Bulgaria

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Author Biographies

  • Elitsa Panayotova, National Centre of Infectious and Parasitic Diseases

    National reference laboratory of vector-borne infections, listeria and leptospires

  • Prof. Iva Christova, MD, National Centre of Infectious and Parasitic Diseases

    Head of National reference laboratory of vector-borne infections, listeria and leptospires

  • Iva Trifonova, National Centre of Infectious and Parasitic Diseases

    National reference laboratory of vector-borne infections, listeria and leptospires

  • Evgenia Taseva, National Centre of Infectious and Parasitic Diseases

    National reference laboratory of vector-borne infections, listeria and leptospires

  • Teodora Gladnishka, National Centre of Infectious and Parasitic Diseases

    National reference laboratory of vector-borne infections, listeria and leptospires

  • Vladislava Ivanova, National Centre of Infectious and Parasitic Diseases

    National reference laboratory of vector-borne infections, listeria and leptospires

References

Christova I, Panayotova E, Tchakarova S, Taseva E, Trifonova I, Gladnishka T. A nationwide seroprevalence screening for West Nile virus and Tick-borne encephalitis virus in the population of Bulgaria. J Med Virol. 2017; 89(10):1875-1878. DOI: https://doi.org/10.1002/jmv.24855

Christova I, Panayotova E, Trifonova I, Taseva E, Gladnishka T. Unexpectedly high number of West Nile neuroinvasive diseases in Bulgaria in 2018. Probl Infect Parasit Dis. 2018; 46(2):16-19. DOI: https://doi.org/10.58395/pipd.v46i2.19

Ergunay K, Bakonyi T, Nowotny N, Ozkul A. Close relationship between West Nile virus from Turkey and lineage 1 strain from Central African Republic. Emerg Infect Dis. 2015; 21(2):352-355. DOI: https://doi.org/10.3201/eid2102.141135

Lustig Y, Sofer D, Bucris ED, Mendelson E. Surveillance and Diagnosis of West Nile Virus in the Face of Flavivirus Cross-Reactivity. Front Microbiol. 2018; 9:2421. DOI: https://doi.org/10.3389/fmicb.2018.02421

Petrović T, Šekler M, Petrić D, Lazić S, Debeljak Z, Vidanović D, et al. Methodology and results of integrated WNV surveillance programmes in Serbia. PLoS ONE. 2018; 13(4):e0195439. DOI: https://doi.org/10.1371/journal.pone.0195439

Tsai TF, Popovici F, Cernescu C, Campbell GL, Nedelcu NI. West Nile encephalitis epidemic in southeastern Romania. Lancet. 1998;352(9130):767-771. DOI: https://doi.org/10.1016/S0140-6736(98)03538-7

Popescu CP, Florescu SA, Badescu D, Ceianu CS, Zaharia M, Tardei G, Codreanu D, Ceausu E, Ruta SM. Re-emergence of severe West Nile virus neuroinvasive disease in humans in Romania, 2012 to 2017 – implications for travel medicine. Travel Med Infect Dis. 2018; 22:30-35. DOI: https://doi.org/10.1016/j.tmaid.2018.03.001

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Published

2019-12-30

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Articles

How to Cite

(1)
Panayotova, E.; Christova, I.; Trifonova, I.; Taseva, E.; Gladnishka, T.; Ivanova, V. SEROPREVALENCE OF WEST NILE VIRUS IN BULGARIA, 2018. Probl Infect Parasit Dis 2019, 47 (2), 15-17. https://doi.org/10.58395/pipd.v47i2.6.

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