E. VERMICULARIS – PROSPECTS FOR FUTURE RESEARCH
A BRIEF LITERATURE REVIEW
DOI:
https://doi.org/10.58395/pipd.v50i2.92Keywords:
Enterobius vermicularis, molecular characterization, cox1 gene, intestinal imbalanceAbstract
Enterobius vermicularis is an intestinal parasite with a cosmopolitan distribution and the disease which causes (enterobiasis) is one of the most common helminth infection worldwide. According to literature data it affects nearly 1 billion people and is found in various socio-economic groups. Everyone is susceptible to infection, but children are more often affected than adults due to their poorly developed hygiene habits. Patients with enterobiasis are often reinfected which together with the high endurance of the pinworm eggs in the environment contributes to the difficult control of the disease. In recent decades, a number of studies have been conducted on the genotypic characteristics of the nematode, including sequencing, which accumulates data on phylogenetic varieties of the species to improve the diagnosis and control of this infection in humans.
The available data reveal influence of E. vermicularis on the local immunity of intestinal mucosa in infected individuals, but these data are scarce and contradictory and do not clarify the significance of this influence on the clinical manifestations of the disease. Additional studies are needed to define the relationship of this effect with the clinical symptoms of the disease.
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Copyright (c) 2023 Eleonora Kaneva, Rumen Harizanov, Nina Tsvetkova, Iskren Kaftanjiev, Raina Borisova, Aleksandra Ivanova, Mihaela Videnova, Desislava Velcheva, Ivailo Alexiev, Reneta Dimitrova, Maria Pavlova, Ekaterina Aleksandrova (Author)
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